Threeyearsafterkillingthevampireintheoriginal,Charliehasstartedtobelieveitwasallhisimaginationandstartstoforgetthatvampirestrulyexist-untilfourstrangersleadbyRegina,anotedactress,arrivesatPeterVincent'shouseandstartstohaveanunhealthyinterestinCharlie,PeterandCharlie'snewgirlfriendAlex.ItbecomesclearthatReginaisJerry'ssisterandsheisdeterminedtogetrevengeonthefriendsandplanstoturnCharlieintoavampire-sothathecanfacehispunishmentforalleternity.
